To replicate or not to replicate: achieving selective oncolytic virus replication in cancer cells through translational control

To replicate or not to replicate: the case of pharmacogenetic studies: Establishing validity of pharmacogenomic findings: from replication to triangulation.

To Replicate or Not To Replicate Queries in the Presence of Autonomous Participants?

L’objectif d’un système largement distribué sur Internet est d’intégrer des participants dont les spécificités et motivations ne sont pas toujours clairement identifiées a priori. En particulier, des participants autonomes peuvent avoir des intérêts individuels spécifiques vis-à-vis des requêtes, mais aussi des autres participants. Dans un tel contexte, un système ne prenant pas en compte les i...

Cancer virotherapy: Targeting cancer cells by microRNA mechanism for selective replication of oncolytic viruses in these cells

Cancer, as one of the most serious public health problems, is the second-leading cause of death in the world after cardiovascular disease. The number of patients and the resulting mortality are increasing worldwide; therefore, early diagnosis, prevention, and effective treatment of cancer are very important. Current treatments such as chemotherapy and radiation therapy are often non-selective a...

To replicate or not to replicate: the case of pharmacogenetic studies: Have pharmacogenomics failed, or do they just need larger-scale evidence and more replication?

Replicate or lie.

Andrén and colleagues (2008) recently published a paper reminding us of good scientific practice, taught and learnt during our early years of research, but frequently forgotten. This article has a similar objective. It is highly likely that the majority of microbial ecologists have taken a basic course in statistics. Unfortunately, the basic principles of statistical analysis and its significan...